Basal Cell Carcinoma Arising from Xeroderma Pigmentosum: A Case Report and an Immunohistochemical Study
نویسندگان
چکیده
We describe a 26-year-old Japanese patient with basal cell carcinoma arising from xeroderma pigmentosum (XP). Immunohistochemical staining revealed dense infiltration of CD163(+) M2 macrophages, together with Foxp3(+) regulatory T cells. Interestingly, MMP9, which was reported as one of the functional markers for immunosuppressive macrophages, was also detected in the CD163(+) M2 macrophage-infiltrated areas. Our case suggests the immunological background of tumor development in a patient with XP.
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عنوان ژورنال:
دوره 5 شماره
صفحات -
تاریخ انتشار 2013